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Switchable CAR T cell strategy against osteosarcoma

Immunotherapy with chimeric antigen receptor T (CAR T) cells has changed the treatment of hematological malignances, but they are still a challenge for solid tumors, including pediatric sarcomas. Here, we report a switchable CAR T cell strategy based on anti-FITC CAR T cells and a switch molecule co...

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Detalles Bibliográficos
Autores principales: Hidalgo, Laura, Somovilla-Crespo, Beatriz, Garcia-Rodriguez, Patricia, Morales-Molina, Alvaro, Rodriguez-Milla, Miguel Angel, Garcia-Castro, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361906/
https://www.ncbi.nlm.nih.gov/pubmed/37062034
http://dx.doi.org/10.1007/s00262-023-03437-z