JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis

Oncogenic super-enhancers (SEs) generate noncoding enhancer/SE RNAs (eRNAs/seRNAs) that exert a critical function in malignancy through powerful regulation of target gene expression. Herein, we show that a JUN-mediated seRNA can form R-loop to regulate target genes to promote metastasis of nasophary...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Qunying, Tan, Yuan, Li, Yuejin, Wu, Yao, Wang, Jing, Tang, Faqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361959/
https://www.ncbi.nlm.nih.gov/pubmed/37479693
http://dx.doi.org/10.1038/s41419-023-05985-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361959/
https://www.ncbi.nlm.nih.gov/pubmed/37479693
http://dx.doi.org/10.1038/s41419-023-05985-9

Ejemplares similares