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JUN-induced super-enhancer RNA forms R-loop to promote nasopharyngeal carcinoma metastasis
Oncogenic super-enhancers (SEs) generate noncoding enhancer/SE RNAs (eRNAs/seRNAs) that exert a critical function in malignancy through powerful regulation of target gene expression. Herein, we show that a JUN-mediated seRNA can form R-loop to regulate target genes to promote metastasis of nasophary...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361959/ https://www.ncbi.nlm.nih.gov/pubmed/37479693 http://dx.doi.org/10.1038/s41419-023-05985-9 |