STAG2 inactivation reprograms glutamine metabolism of BRAF-mutant thyroid cancer cells

STAG2, an important subunit in cohesion complex, is involved in the segregation of chromosomes during the late mitosis and the formation of sister chromatids. Mutational inactivation of STAG2 is a major cause of the resistance of BRAF-mutant melanomas to BRAF/MEK inhibitors. In the present study, we...

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Detalles Bibliográficos
Autores principales: Li, Xinru, Liu, Yan, Liu, Juan, Qiang, Wei, Ma, Jingjing, Xie, Jingyi, Chen, Pu, Wang, Yubo, Hou, Peng, Ji, Meiju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361981/
https://www.ncbi.nlm.nih.gov/pubmed/37479689
http://dx.doi.org/10.1038/s41419-023-05981-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10361981/
https://www.ncbi.nlm.nih.gov/pubmed/37479689
http://dx.doi.org/10.1038/s41419-023-05981-z

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