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NVS-ZP7-4 inhibits hepatocellular carcinoma tumorigenesis and promotes apoptosis via PI3K/AKT signaling

NVS-ZP7-4 was identified as a novel chemical reagent targeting the zinc input protein ZIP7, which accounts for the zinc surge from the apparatus to the cytoplasm. Since zinc dysregulation is related to multiple diseases, in this study, we aimed to identify the anti-tumor effects of NVS-ZP7-4 and exp...

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Detalles Bibliográficos
Autores principales: Tong, Qing, Yan, Dong, Cao, Yan, Dong, Xiaogang, Abula, Yimamumaimaitijiang, Yang, Huan, Kong, Panpan, Yi, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362011/
https://www.ncbi.nlm.nih.gov/pubmed/37479837
http://dx.doi.org/10.1038/s41598-023-38596-7