Human PNPase causes RNA stabilization and accumulation of R-loops in the Escherichia coli model system

Polyribonucleotide phosphorylase (PNPase) is a phosphorolytic RNA exonuclease highly conserved throughout evolution. In Escherichia coli, PNPase controls complex phenotypic traits like biofilm formation and growth at low temperature. In human cells, PNPase is located in mitochondria, where it is imp...

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Detalles Bibliográficos
Autores principales: Falchi, Federica A., Forti, Francesca, Carnelli, Cristina, Genco, Aurelia, Pizzoccheri, Roberto, Manzari, Caterina, Pavesi, Giulio, Briani, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362022/
https://www.ncbi.nlm.nih.gov/pubmed/37479726
http://dx.doi.org/10.1038/s41598-023-38924-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362022/
https://www.ncbi.nlm.nih.gov/pubmed/37479726
http://dx.doi.org/10.1038/s41598-023-38924-x

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