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SuPAR mediates viral response proteinuria by rapidly changing podocyte function

Elevation in soluble urokinase receptor (suPAR) and proteinuria are common signs in patients with moderate to severe coronavirus disease 2019 (COVID-19). Here we characterize a new type of proteinuria originating as part of a viral response. Inoculation of severe acute respiratory syndrome coronavir...

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Detalles Bibliográficos
Autores principales: Wei, Changli, Datta, Prasun K., Siegerist, Florian, Li, Jing, Yashwanth, Sudhini, Koh, Kwi Hye, Kriho, Nicholas W., Ismail, Anis, Luo, Shengyuan, Fischer, Tracy, Amber, Kyle T., Cimbaluk, David, Landay, Alan, Endlich, Nicole, Rappaport, Jay, Hayek, Salim S., Reiser, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362037/
https://www.ncbi.nlm.nih.gov/pubmed/37479685
http://dx.doi.org/10.1038/s41467-023-40165-5