Cargando…

SuPAR mediates viral response proteinuria by rapidly changing podocyte function

Elevation in soluble urokinase receptor (suPAR) and proteinuria are common signs in patients with moderate to severe coronavirus disease 2019 (COVID-19). Here we characterize a new type of proteinuria originating as part of a viral response. Inoculation of severe acute respiratory syndrome coronavir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wei, Changli, Datta, Prasun K., Siegerist, Florian, Li, Jing, Yashwanth, Sudhini, Koh, Kwi Hye, Kriho, Nicholas W., Ismail, Anis, Luo, Shengyuan, Fischer, Tracy, Amber, Kyle T., Cimbaluk, David, Landay, Alan, Endlich, Nicole, Rappaport, Jay, Hayek, Salim S., Reiser, Jochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362037/ https://www.ncbi.nlm.nih.gov/pubmed/37479685 http://dx.doi.org/10.1038/s41467-023-40165-5

Ejemplares similares

suPAR: An Inflammatory Mediator for Kidneys
por: Sudhini, Yashwanth Reddy, et al.
Publicado: (2022)

suPAR and WT1 modify the adhesion of podocytes and are related to proteinuria in class IV lupus nephritis
por: Bollain-y-Goytia, Juan-José, et al.
Publicado: (2023)

suPAR, a Circulating Kidney Disease Factor
por: Wei, Changli, et al.
Publicado: (2021)

Novel Microscopic Techniques for Podocyte Research
por: Siegerist, Florian, et al.
Publicado: (2018)

Reassessing the Reassessment of suPAR in Glomerular Disease
por: Meijers, Björn K. I., et al.
Publicado: (2015)

Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae
por: Siegerist, Florian, et al.
Publicado: (2017)

Cardiovascular Disease Biomarkers and suPAR in Predicting Decline in Renal Function: A Prospective Cohort Study
por: Hayek, Salim S., et al.
Publicado: (2017)

Assay-related differences in SuPAR levels: implications for measurement and data interpretation
por: Vasbinder, Alexi, et al.
Publicado: (2022)

Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
por: Agarwal, Shivangi, et al.
Publicado: (2021)

suPAR and Team Nephrology
por: Trachtman, Howard
Publicado: (2014)

Fetal Renal Echogenicity Associated with Maternal Focal Segmental Glomerulosclerosis: The Effect of Transplacental Transmission of Permeability Factor suPAR
por: Shuster, Shirley, et al.
Publicado: (2018)

Monitoring suPAR levels in post-kidney transplant focal segmental glomerulosclerosis treated with therapeutic plasma exchange and rituximab
por: Alachkar, Nada, et al.
Publicado: (2018)

Soluble urokinase plasminogen activator receptor (suPAR) as an early predictor of severe respiratory failure in patients with COVID-19 pneumonia
por: Rovina, Nikoletta, et al.
Publicado: (2020)

suPAR: The Molecular Crystal Ball
por: Thunø, Maria, et al.
Publicado: (2009)

suPAR links a dysregulated immune response to tissue inflammation and sepsis-induced acute kidney injury
por: Nusshag, Christian, et al.
Publicado: (2023)

Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement
por: Siegerist, Florian, et al.
Publicado: (2017)

Role of the podocyte in proteinuria
por: Menzel, Sylvia, et al.
Publicado: (2011)

Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy
por: Artelt, Nadine, et al.
Publicado: (2018)

suPAR as a prognostic biomarker in sepsis
por: Donadello, Katia, et al.
Publicado: (2012)

suPAR to Risk-Stratify Patients With Malaria
por: Stefanova, Veselina, et al.
Publicado: (2022)

Kidney-derived c-kit(+) progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria
por: Rangel, Erika B., et al.
Publicado: (2018)

1,25-Dihydroxyvitamin D(3) Inhibits Podocyte uPAR Expression and Reduces Proteinuria
por: Ma, Jianchao, et al.
Publicado: (2013)

Sex Differences in Circulating Soluble Urokinase‐Type Plasminogen Activator Receptor (suPAR) Levels and Adverse Outcomes in Coronary Artery Disease
por: Mehta, Anurag, et al.
Publicado: (2020)

Elevated suPAR Is an Independent Risk Marker for Incident Kidney Disease in Acute Medical Patients
por: Iversen, Esben, et al.
Publicado: (2020)

The Association of uPA, uPAR, and suPAR System with Inflammation and Joint Damage in Rheumatoid Arthritis: suPAR as a Biomarker in the Light of a Personalized Medicine Perspective
por: Benucci, Maurizio, et al.
Publicado: (2022)

SuPAR - A future prognostic biomarker in emergency medicine
por: Østervig, Rebecca M, et al.
Publicado: (2015)

Soluble Urokinase Plasminogen Activator Receptor (suPAR) and All-Cause and Cardiovascular Mortality in Diverse Hemodialysis Patients
por: Torino, Claudia, et al.
Publicado: (2018)

suPAR remains uninfluenced by surgery in septic patients with bloodstream infection
por: Rabensteiner, Jasmin, et al.
Publicado: (2016)

Kinetics of the soluble urokinase plasminogen activator receptor (suPAR) in cirrhosis
por: Garnæs, Emilie, et al.
Publicado: (2019)

suPAR Surprises as a Biomarker of Invasive Outcomes in Pleural Infection
por: Idell, Steven, et al.
Publicado: (2020)

The Perspective of Vitamin D on suPAR-Related AKI in COVID-19
por: Liao, Tzu-Hsien, et al.
Publicado: (2022)

The Association of suPAR with Cardiovascular Risk Factors in Young and Healthy Adults
por: Wohlwend, Niklas Fabio, et al.
Publicado: (2023)

Super‐resolved local recruitment of CLDN5 to filtration slits implicates a direct relationship with podocyte foot process effacement
por: Tesch, Florian, et al.
Publicado: (2021)

Detection of suPAR in the Saliva of Healthy Young Adults: Comparison with Plasma Levels
por: Gustafsson, Anna, et al.
Publicado: (2011)

SuPAR predicts postoperative complications and mortality in patients with asymptomatic aortic stenosis
por: Hodges, Gethin W, et al.
Publicado: (2018)

Plasma levels of the active form of suPAR are associated with COVID-19 severity
por: Huang, Mingxiang, et al.
Publicado: (2020)

suPAR Cut-Offs for Risk Stratification in Patients With Symptoms of COVID-19
por: Altintas, Izzet, et al.
Publicado: (2021)

Predictive value of suPAR in AKI: a systematic review and meta-analysis
por: Huang, Yan, et al.
Publicado: (2022)

Soluble urokinase plasminogen activator receptor (suPAR) in the emergency department: An update
por: Velissaris, Dimitrios, et al.
Publicado: (2022)

The Prognostic Value of suPAR Compared to Other Inflammatory Markers in Patients with Severe Sepsis
por: Gustafsson, Anna, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_ia78vc6n5s179m4i3mtkis839v