Elastin stabilization prevents impaired biomechanics in human pulmonary arteries and pulmonary hypertension in rats with left heart disease

Pulmonary hypertension worsens outcome in left heart disease. Stiffening of the pulmonary artery may drive this pathology by increasing right ventricular dysfunction and lung vascular remodeling. Here we show increased stiffness of pulmonary arteries from patients with left heart disease that correl...

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Detalles Bibliográficos
Autores principales: Kucherenko, Mariya M., Sang, Pengchao, Yao, Juquan, Gransar, Tara, Dhital, Saphala, Grune, Jana, Simmons, Szandor, Michalick, Laura, Wulsten, Dag, Thiele, Mario, Shomroni, Orr, Hennig, Felix, Yeter, Ruhi, Solowjowa, Natalia, Salinas, Gabriela, Duda, Georg N., Falk, Volkmar, Vyavahare, Naren R., Kuebler, Wolfgang M., Knosalla, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362055/
https://www.ncbi.nlm.nih.gov/pubmed/37479718
http://dx.doi.org/10.1038/s41467-023-39934-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362055/
https://www.ncbi.nlm.nih.gov/pubmed/37479718
http://dx.doi.org/10.1038/s41467-023-39934-z

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