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ATAD2 is a driver and a therapeutic target in ovarian cancer that functions by upregulating CENPE

Ovarian cancer is a complex disease associated with multiple genetic and epigenetic alterations. The emergence of treatment resistance in most patients causes ovarian cancer to become incurable, and novel therapies remain necessary. We identified epigenetic regulator ATPase family AAA domain-contain...

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Detalles Bibliográficos
Autores principales: Guruvaiah, Praveen, Chava, Suresh, Sun, Chiao-Wang, Singh, Nirupama, Penn, Courtney A., Gupta, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362061/
https://www.ncbi.nlm.nih.gov/pubmed/37479754
http://dx.doi.org/10.1038/s41419-023-05993-9