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MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters

Histone H4 lysine 16 acetylation (H4K16ac), governed by the histone acetyltransferase MOF, orchestrates gene expression regulation and chromatin interaction. However, the roles of MOF and H4K16ac in controlling cellular function and regulating mammalian tissue development remain unclear. Here we sho...

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Detalles Bibliográficos
Autores principales: Wang, Dongmei, Li, Haimin, Chandel, Navdeep S., Dou, Yali, Yi, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362062/
https://www.ncbi.nlm.nih.gov/pubmed/37479688
http://dx.doi.org/10.1038/s41467-023-40108-0