Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire

Variation in the antibody response has been linked to differential outcomes in disease, and suboptimal vaccine and therapeutic responsiveness, the determinants of which have not been fully elucidated. Countering models that presume antibodies are generated largely by stochastic processes, we demonst...

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Detalles Bibliográficos
Autores principales: Rodriguez, Oscar L., Safonova, Yana, Silver, Catherine A., Shields, Kaitlyn, Gibson, William S., Kos, Justin T., Tieri, David, Ke, Hanzhong, Jackson, Katherine J. L., Boyd, Scott D., Smith, Melissa L., Marasco, Wayne A., Watson, Corey T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362067/
https://www.ncbi.nlm.nih.gov/pubmed/37479682
http://dx.doi.org/10.1038/s41467-023-40070-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362067/
https://www.ncbi.nlm.nih.gov/pubmed/37479682
http://dx.doi.org/10.1038/s41467-023-40070-x

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