Monitoring RNA restructuring in a human cell-free extract reveals eIF4A-dependent and eIF4A-independent unwinding activity

The canonical DEAD-box helicase, eukaryotic initiation factor (eIF) 4A, unwinds 5′ UTR secondary structures to promote mRNA translation initiation. Growing evidence has indicated that other helicases, such as DHX29 and DDX3/ded1p, also function to promote the scanning of the 40S subunit on highly st...

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Detalles Bibliográficos
Autores principales: O'Sullivan, Mattie H., Fraser, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362145/
https://www.ncbi.nlm.nih.gov/pubmed/37331603
http://dx.doi.org/10.1016/j.jbc.2023.104936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362145/
https://www.ncbi.nlm.nih.gov/pubmed/37331603
http://dx.doi.org/10.1016/j.jbc.2023.104936

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