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Protocol for inducing branching morphogenesis in human cholangiocyte and cholangiocarcinoma organoids

Bile ducts are essential for bile transport and consist of complex branching tubular networks. Human patient-derived cholangiocyte develops a cystic rather than branching duct morphology. Here, we present a protocol to establish branching morphogenesis in cholangiocyte and cholangiocarcinoma organoi...

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Detalles Bibliográficos
Autores principales: Ober, Kimberley, Roos, Floris J.M., van Tienderen, Gilles S., Köten, Kübra, Klaassen, Annelot, Mi, Wunan, van der Laan, Luc J.W., Verstegen, Monique M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362172/
https://www.ncbi.nlm.nih.gov/pubmed/37432852
http://dx.doi.org/10.1016/j.xpro.2023.102431