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Selenium-binding protein 1 (SELENBP1) is a copper-dependent thiol oxidase

Selenium-binding protein 1 (SELENBP1) was reported to act as a methanethiol oxidase (MTO) in humans, catalyzing the conversion of methanethiol to hydrogen peroxide, hydrogen sulfide and formaldehyde. Here, we identify copper ions as essential to this novel MTO activity. Site-directed mutagenesis of...

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Detalles Bibliográficos
Autores principales: Philipp, Thilo Magnus, Gernoth, Leon, Will, Andreas, Schwarz, Maria, Ohse, Verena Alexia, Kipp, Anna Patricia, Steinbrenner, Holger, Klotz, Lars-Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362175/
https://www.ncbi.nlm.nih.gov/pubmed/37437449
http://dx.doi.org/10.1016/j.redox.2023.102807