Opposing effects of KDM6A and JDP2 on glucocorticoid sensitivity in T-ALL

Glucocorticoids (GCs) are the cornerstone of acute lymphoblastic leukemia (ALL) therapy. Although mutations in NR3C1, which encodes the GC receptor (GR), and other genes involved in GC signaling occur at relapse, additional mechanisms of adaptive GC resistance are uncertain. We transplanted and trea...

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Detalles Bibliográficos
Autores principales: Levinson, Anya L., Tjoa, Karensa, Huang, Benjamin, Meyer, Lauren K., Kim, Mi-Ok, Brady, Samuel W., Zhang, Jinghui, Shannon, Kevin, Wandler, Anica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Lymphoid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362263/
https://www.ncbi.nlm.nih.gov/pubmed/36897249
http://dx.doi.org/10.1182/bloodadvances.2021006881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362263/
https://www.ncbi.nlm.nih.gov/pubmed/36897249
http://dx.doi.org/10.1182/bloodadvances.2021006881

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