DNA facilitates heterodimerization between human transcription factors FoxP1 and FoxP2 by increasing their conformational flexibility

Transcription factors regulate gene expression by binding to DNA. They have disordered regions and specific DNA-binding domains. Binding to DNA causes structural changes, including folding and interactions with other molecules. The FoxP subfamily of transcription factors in humans is unique because...

Descripción completa

Detalles Bibliográficos
Autores principales: Coñuecar, Ricardo, Asela, Isabel, Rivera, Maira, Galaz-Davison, Pablo, González-Higueras, Jorge, Hamilton, George L., Engelberger, Felipe, Ramírez-Sarmiento, César A., Babul, Jorge, Sanabria, Hugo, Medina, Exequiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362293/
https://www.ncbi.nlm.nih.gov/pubmed/37485372
http://dx.doi.org/10.1016/j.isci.2023.107228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362293/
https://www.ncbi.nlm.nih.gov/pubmed/37485372
http://dx.doi.org/10.1016/j.isci.2023.107228

Ejemplares similares