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Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation

Alcohol is among the most widely consumed dietary substances. Excessive alcohol consumption damages the liver, heart, and brain. Alcohol also has strong immunoregulatory properties. Here, we report how alcohol impairs T cell function via acetylation of cortactin, a protein that binds filamentous act...

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Detalles Bibliográficos
Autores principales: Azizov, Vugar, Hübner, Michel, Frech, Michael, Hofmann, Jörg, Kubankova, Marketa, Lapuente, Dennis, Tenbusch, Matthias, Guck, Jochen, Schett, Georg, Zaiss, Mario M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362326/
https://www.ncbi.nlm.nih.gov/pubmed/37485352
http://dx.doi.org/10.1016/j.isci.2023.107230