Cargando…

DIRAS3 enhances RNF19B-mediated RAC1 ubiquitination and degradation in non-small-cell lung cancer cells

Distant metastasis remains the leading cause of high mortality in patients with non-small-cell lung cancer (NSCLC). DIRAS3 is a candidate tumor suppressor protein that is decreased in various tumors. However, the regulatory mechanism of DIRAS3 on metastasis of NSCLC remains unclear. Here, we found t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yingying, Wei, Minli, Su, Min, Du, Zhiyuan, Dong, Jiaxi, Zhang, Yu, Wu, Yingdi, Li, Xiaopeng, Su, Ling, Liu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362343/
https://www.ncbi.nlm.nih.gov/pubmed/37485351
http://dx.doi.org/10.1016/j.isci.2023.107157