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Increased α-HB links colorectal cancer and diabetes by potentiating NF-κB signaling

Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanisms are not fully understood. α-Hydroxybutyrate (α-HB), a byproduct metabolite increased in diabetes and cancer, including colorectal cancer (CRC), triggers lactate dehy...

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Detalles Bibliográficos
Autores principales: Lv, Xinyue, Ding, Peipei, Li, Luying, Li, Ling, Zhou, Danlei, Wang, Xiaochao, Chen, Jianfeng, Zhang, Wei, Wang, Qi, Liao, Tian, Wen, Wenyu, Zhou, Dawang, Ji, Qing-Hai, He, Xianghuo, Lei, Qun-Ying, Hu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362362/
https://www.ncbi.nlm.nih.gov/pubmed/37406987
http://dx.doi.org/10.1016/j.molmet.2023.101766