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Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B

Sarcomeres are fundamental to cardiac muscle contraction. Their impairment can elicit cardiomyopathies, leading causes of death worldwide. However, the molecular mechanism underlying sarcomere assembly remains obscure. We used human embryonic stem cell (hESC)-derived cardiomyocytes (CMs) to reveal s...

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Detalles Bibliográficos
Autores principales: Lu, Serena Huei-An, Wu, Yi-Hsuan, Su, Liang-Yu, Hsu, Zi-Ting, Weng, Tzu-Han, Wang, Hsin-Yu, Yu, Chiao, Hsu, Paul Wei-Che, Tsai, Su-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362501/
https://www.ncbi.nlm.nih.gov/pubmed/37295424
http://dx.doi.org/10.1016/j.stemcr.2023.05.006