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Cardiac myofibrillogenesis is spatiotemporally modulated by the molecular chaperone UNC45B
Sarcomeres are fundamental to cardiac muscle contraction. Their impairment can elicit cardiomyopathies, leading causes of death worldwide. However, the molecular mechanism underlying sarcomere assembly remains obscure. We used human embryonic stem cell (hESC)-derived cardiomyocytes (CMs) to reveal s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362501/ https://www.ncbi.nlm.nih.gov/pubmed/37295424 http://dx.doi.org/10.1016/j.stemcr.2023.05.006 |