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Current progress, challenges, and future perspectives of language models for protein representation and protein design

The sequence-structure-function paradigm of protein is the basis of molecular biology. What is the underlying mechanism of such sequence and structure/function corresponding relationship? We reviewed the methods for protein representation and protein design. With these protein representation models,...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Li, Yixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362512/
https://www.ncbi.nlm.nih.gov/pubmed/37485078
http://dx.doi.org/10.1016/j.xinn.2023.100446