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Hypoxia-based classification and prognostic signature for clinical management of hepatocellular carcinoma

OBJECTIVE: Intratumoral hypoxia is an essential feature of hepatocellular carcinoma (HCC). Herein, we investigated the hypoxia-based heterogeneity and relevant clinical implication in HCC. METHODS: Three HCC cohorts: TCGA-LIHC, LICA-FR, and LIRI-JP were retrospectively gathered. Consensus clustering...

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Detalles Bibliográficos
Autores principales: Li, Ke, Yang, Yanfang, Ma, Mingwei, Lu, Suping, Li, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362578/
https://www.ncbi.nlm.nih.gov/pubmed/37481543
http://dx.doi.org/10.1186/s12957-023-03090-x