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GDF-11 downregulates placental human chorionic gonadotropin expression by activating SMAD2/3 signaling
BACKGROUND: The production of human chorionic gonadotropin (hCG) by the placental trophoblast cells is essential for maintaining a normal pregnancy. Aberrant hCG levels are associated with reproductive disorders. The protein of hCG is a dimer consisting of an α subunit and a β subunit. The β subunit...
Autores principales: | Wu, Ze, Zhang, Lingling, Jia, Yuanyuan, Bi, Beibei, Fang, Lanlan, Cheng, Jung-Chien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362589/ https://www.ncbi.nlm.nih.gov/pubmed/37480123 http://dx.doi.org/10.1186/s12964-023-01201-5 |
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