Beyond canonical PROTAC: biological targeted protein degradation (bioTPD)

Targeted protein degradation (TPD) is an emerging therapeutic strategy with the potential to modulate disease-associated proteins that have previously been considered undruggable, by employing the host destruction machinery. The exploration and discovery of cellular degradation pathways, including b...

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Detalles Bibliográficos
Autores principales: Wang, Huifang, Zhou, Runhua, Xu, Fushan, Yang, Kongjun, Zheng, Liuhai, Zhao, Pan, Shi, Guangwei, Dai, Lingyun, Xu, Chengchao, Yu, Le, Li, Zhijie, Wang, Jianhong, Wang, Jigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362593/
https://www.ncbi.nlm.nih.gov/pubmed/37480049
http://dx.doi.org/10.1186/s40824-023-00385-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362593/
https://www.ncbi.nlm.nih.gov/pubmed/37480049
http://dx.doi.org/10.1186/s40824-023-00385-8

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