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N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope

Fibroblast growth factor receptor 1 (FGFR1) is a heavily N-glycosylated cell surface receptor tyrosine kinase that transmits signals across the plasma membrane, in response to fibroblast growth factors (FGFs). Balanced FGF/FGFR1 signaling is crucial for the development and homeostasis of the human b...

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Detalles Bibliográficos
Autores principales: Gregorczyk, Paulina, Porębska, Natalia, Żukowska, Dominika, Chorążewska, Aleksandra, Gędaj, Aleksandra, Malinowska, Agata, Otlewski, Jacek, Zakrzewska, Małgorzata, Opaliński, Łukasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362638/
https://www.ncbi.nlm.nih.gov/pubmed/37480072
http://dx.doi.org/10.1186/s12964-023-01203-3