Cargando…
N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope
Fibroblast growth factor receptor 1 (FGFR1) is a heavily N-glycosylated cell surface receptor tyrosine kinase that transmits signals across the plasma membrane, in response to fibroblast growth factors (FGFs). Balanced FGF/FGFR1 signaling is crucial for the development and homeostasis of the human b...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362638/ https://www.ncbi.nlm.nih.gov/pubmed/37480072 http://dx.doi.org/10.1186/s12964-023-01203-3 |