Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop

BACKGROUND: The immunosuppressive microenvironment in glioma induces immunotherapy resistance and is associated with poor prognosis. Glioma-associated mesenchymal stem cells (GA-MSCs) play an important role in the formation of the immunosuppressive microenvironment, but the mechanism is still not cl...

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Detalles Bibliográficos
Autores principales: Qiu, Wei, Guo, Qindong, Guo, Xiaofan, Wang, Chaochao, Li, Boyan, Qi, Yanhua, Wang, Shaobo, Zhao, Rongrong, Han, Xiao, Du, Hao, Zhao, Shulin, Pan, Ziwen, Fan, Yang, Wang, Qingtong, Gao, Zijie, Li, Gang, Xue, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362641/
https://www.ncbi.nlm.nih.gov/pubmed/37481646
http://dx.doi.org/10.1186/s12951-023-01997-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362641/
https://www.ncbi.nlm.nih.gov/pubmed/37481646
http://dx.doi.org/10.1186/s12951-023-01997-x

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