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Searching for protein variants with desired properties using deep generative models
BACKGROUND: Protein engineering aims to improve the functional properties of existing proteins to meet people’s needs. Current deep learning-based models have captured evolutionary, functional, and biochemical features contained in amino acid sequences. However, the existing generative models need t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362698/ https://www.ncbi.nlm.nih.gov/pubmed/37480001 http://dx.doi.org/10.1186/s12859-023-05415-9 |