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SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes

BACKGROUND: Diabetes is associated with an increased risk of cognitive decline and dementia. These diseases are linked with mitochondrial dysfunction, most likely as a consequence of excessive formation of mitochondria-associated membranes (MAMs). Sirtuin3 (SIRT3), a key mitochondrial NAD(+)-depende...

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Detalles Bibliográficos
Autores principales: Chang, Yanmin, Wang, Cailin, Zhu, Jiahui, Zheng, Siyi, Sun, Shangqi, Wu, Yanqing, Jiang, Xingjun, Li, Lulu, Ma, Rong, Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362714/
https://www.ncbi.nlm.nih.gov/pubmed/37481555
http://dx.doi.org/10.1186/s12967-023-04246-9