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mRNA sequencing reveals the distinct gene expression and biological functions in cardiac fibroblasts regulated by recombinant fibroblast growth factor 2

After myocardial injury, cardiac fibroblasts (CFs) differentiate into myofibroblasts, which express and secrete extracellular matrix (ECM) components for myocardial repair, but also promote myocardial fibrosis. Recombinant fibroblast growth factor 2 (FGF2) protein drug with low molecular weight can...

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Detalles Bibliográficos
Autores principales: Sun, Changye, Bai, Mengru, Jia, Yangyang, Tian, Xiangqin, Guo, Yonglong, Xu, Xinhui, Guo, Zhikun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10362857/
https://www.ncbi.nlm.nih.gov/pubmed/37483983
http://dx.doi.org/10.7717/peerj.15736