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CNAsim: improved simulation of single-cell copy number profiles and DNA-seq data from tumors

SUMMARY: CNAsim is a software package for improved simulation of single-cell copy number alteration (CNA) data from tumors. CNAsim can be used to efficiently generate single-cell copy number profiles for thousands of simulated tumor cells under a more realistic error model and a broader range of pos...

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Detalles Bibliográficos
Autores principales: Weiner, Samson, Bansal, Mukul S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363024/
https://www.ncbi.nlm.nih.gov/pubmed/37449891
http://dx.doi.org/10.1093/bioinformatics/btad434