Myeloid-derived suppressor cells impair CD4+ T cell responses during chronic Staphylococcus aureus infection via lactate metabolism

Staphylococcus aureus is an important cause of chronic infections resulting from the failure of the host to eliminate the pathogen. Effective S. aureus clearance requires CD4+ T cell-mediated immunity. We previously showed that myeloid-derived suppressor cells (MDSC) expand during staphylococcal inf...

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Detalles Bibliográficos
Autores principales: Goldmann, Oliver, Medina, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363054/
https://www.ncbi.nlm.nih.gov/pubmed/37480485
http://dx.doi.org/10.1007/s00018-023-04875-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363054/
https://www.ncbi.nlm.nih.gov/pubmed/37480485
http://dx.doi.org/10.1007/s00018-023-04875-9

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