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Targeting Mcl-1 by a small molecule NSC260594 for triple-negative breast cancer therapy

Triple-negative breast cancers (TNBCs) are aggressive forms of breast cancer and tend to grow and spread more quickly than most other types of breast cancer. TNBCs can neither be targeted by hormonal therapies nor the antibody trastuzumab that targets the HER2 protein. There are urgent unmet medical...

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Detalles Bibliográficos
Autores principales: Dong, Shengli, Matossian, Margarite D., Yousefi, Hassan, Khosla, Maninder, Collins-Burow, Bridgette M., Burow, Matthew E., Alahari, Suresh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363135/
https://www.ncbi.nlm.nih.gov/pubmed/37481672
http://dx.doi.org/10.1038/s41598-023-37058-4