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Astragalus Polysaccharide Ameliorates Renal Inflammatory Responses in a Diabetic Nephropathy by Suppressing the TLR4/NF-κB Pathway

BACKGROUND: Diabetic nephropathy (DN), as a chronic inflammatory complication of diabetes, is characterized by hyperglycemia, albuminuria and edema, which ultimately becomes the leading cause of end-stage renal disease (ESRD). Astragalus polysaccharide (APS), extracted from the Astragalus membranace...

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Detalles Bibliográficos
Autores principales: Guo, Mingfei, Gao, Jiarong, Jiang, Lei, Dai, Yaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363349/
https://www.ncbi.nlm.nih.gov/pubmed/37489175
http://dx.doi.org/10.2147/DDDT.S411211