Fabrication and Evaluation of a pH-Responsive Nanocomposite-Based Colonic Delivery System for Improving the Oral Efficacy of Liraglutide

PURPOSE: Oral administration of liraglutide, a protein drug, suffers from low intestinal absorption and instability in the gastrointestinal tract, resulting in low bioavailability. The present study aimed to develop a pH-responsive nanocomposite based-colonic delivery system to improve the oral effi...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Jae Geun, Kim, Da Hyun, Han, Hyo-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363350/
https://www.ncbi.nlm.nih.gov/pubmed/37489139
http://dx.doi.org/10.2147/IJN.S413515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363350/
https://www.ncbi.nlm.nih.gov/pubmed/37489139
http://dx.doi.org/10.2147/IJN.S413515

Ejemplares similares