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M1-Type Macrophages Secrete TNF-α to Stimulate Vascular Calcification by Upregulating CA1 and CA2 Expression in VSMCs

PURPOSE: Vascular calcification is a hallmark of atherosclerosis (AS). We and others confirmed that carbonic anhydrase I (CA1) and CA2 increased expression and catalyzed calcium deposition in atherosclerotic aortas. Macrophages have been demonstrated to be strongly related to AS. This study aimed to...

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Detalles Bibliográficos
Autores principales: Song, Xianqin, Song, Yu, Ma, Quanping, Fang, Kehua, Chang, Xiaotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363393/
https://www.ncbi.nlm.nih.gov/pubmed/37489150
http://dx.doi.org/10.2147/JIR.S413358