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In-depth analysis of the Sirtuin 5-regulated mouse brain malonylome and succinylome using library-free data-independent acquisitions

Post-translational modifications (PTMs) dynamically regulate proteins and biological pathways, typically through the combined effects of multiple PTMs. Lysine residues are targeted for various PTMs, including malonylation and succinylation. However, PTMs offer specific challenges to mass spectrometr...

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Detalles Bibliográficos
Autores principales: Bons, Joanna, Rose, Jacob, Zhang, Ran, Burton, Jordan B, Carrico, Christopher, Verdin, Eric, Schilling, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363399/
https://www.ncbi.nlm.nih.gov/pubmed/36479818
http://dx.doi.org/10.1002/pmic.202100371