Amyloid- β and tau deposition influences cognitive and functional decline in Down syndrome

This study investigates whether tau has (i) an independent effect from amyloid-β on changes in cognitive and functional performance and (ii) a synergistic relationship with amyloid-β in the exacerbation of decline in aging Down syndrome (DS). 105 participants with DS underwent baseline PET [(18)F]-A...

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Detalles Bibliográficos
Autores principales: Grigorova, Monika, Mak, Elijah, Brown, Stephanie S.G., Beresford-Webb, Jessica, Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Tudorascu, Dana, Cohen, Annie, Christian, Bradley T., Ances, Beau, Handen, Benjamin L., Laymon, Charles M., Klunk, William E., Clare, Isabel C.H., Holland, Anthony J., Zaman, Shahid H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363400/
https://www.ncbi.nlm.nih.gov/pubmed/35964542
http://dx.doi.org/10.1016/j.neurobiolaging.2022.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363400/
https://www.ncbi.nlm.nih.gov/pubmed/35964542
http://dx.doi.org/10.1016/j.neurobiolaging.2022.07.003

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