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Semaglutide reduces alcohol intake and relapse-like drinking in male and female rats

BACKGROUND: Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD). However, the probability of low semaglutide doses, an agonist with higher potency and affinity for GLP-1R, to attenuate alcohol...

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Detalles Bibliográficos
Autores principales: Aranäs, Cajsa, Edvardsson, Christian E., Shevchouk, Olesya T., Zhang, Qian, Witley, Sarah, Blid Sköldheden, Sebastian, Zentveld, Lindsay, Vallöf, Daniel, Tufvesson-Alm, Maximilian, Jerlhag, Elisabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363436/
https://www.ncbi.nlm.nih.gov/pubmed/37295046
http://dx.doi.org/10.1016/j.ebiom.2023.104642