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Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer

BACKGROUND: Pyrimidine nucleotides fuel the growth of colorectal cancer (CRC), making their associated proteins potential targets for cancer intervention. Uridine-Cytidine Kinase Like-1(UCKL1) is an enzyme involved in the pyrimidine salvage pathway. It is highly expressed in multiple cancers. But th...

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Detalles Bibliográficos
Autores principales: Wu, Weili, Zhao, Yingying, Qin, Baifu, Jiang, Xin, Wang, Chuyue, Hu, Rong, Ma, Rui, Lee, Mong-Hong, Liu, Huanliang, Li, Kai, Yuan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363437/
https://www.ncbi.nlm.nih.gov/pubmed/37343364
http://dx.doi.org/10.1016/j.ebiom.2023.104650