Apolipoprotein E is required for brain iron homeostasis in mice

BACKGROUND: Apolipoprotein E deficiency (ApoE(−/−)) increases progressively iron in the liver, spleen and aortic tissues with age in mice. However, it is unknown whether ApoE affects brain iron. METHODS: We investigated iron contents, expression of transferrin receptor 1 (TfR1), ferroportin 1 (Fpn1)...

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Detalles Bibliográficos
Autores principales: Ma, Juan, Guo, Qian, Shen, Meng-Qi, Li, Wei, Zhong, Qi-Xin, Qian, Zhong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363452/
https://www.ncbi.nlm.nih.gov/pubmed/37339558
http://dx.doi.org/10.1016/j.redox.2023.102779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363452/
https://www.ncbi.nlm.nih.gov/pubmed/37339558
http://dx.doi.org/10.1016/j.redox.2023.102779

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