Cargando…

Chondroitin Polymerizing Factor (CHPF) promotes cell proliferation and tumor growth in human osteosarcoma by inhibiting SKP2's ubiquitination while activating the AKT pathway

Osteosarcoma is a common malignant tumor occurring in children and young adults. Chondroitin sulfate (CS) participates in cell adhesion, cell division, and the formation of neural networks in the body, the biosynthesis of which requires the participation of glycosyltransferases. CHPF, a glycosyltran...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yi, Li, Jun, Peng, Dan, Liao, Lele, Chen, Xia, Zhong, Weiye, Liu, Zicheng, Yu, Chao, Sun, Yuanliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363583/
https://www.ncbi.nlm.nih.gov/pubmed/37492722
http://dx.doi.org/10.1016/j.gendis.2022.06.010