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Chondroitin Polymerizing Factor (CHPF) promotes cell proliferation and tumor growth in human osteosarcoma by inhibiting SKP2's ubiquitination while activating the AKT pathway
Osteosarcoma is a common malignant tumor occurring in children and young adults. Chondroitin sulfate (CS) participates in cell adhesion, cell division, and the formation of neural networks in the body, the biosynthesis of which requires the participation of glycosyltransferases. CHPF, a glycosyltran...
Autores principales: | Shen, Yi, Li, Jun, Peng, Dan, Liao, Lele, Chen, Xia, Zhong, Weiye, Liu, Zicheng, Yu, Chao, Sun, Yuanliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chongqing Medical University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363583/ https://www.ncbi.nlm.nih.gov/pubmed/37492722 http://dx.doi.org/10.1016/j.gendis.2022.06.010 |
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