FTO-mediated m6A modification alleviates autoimmune uveitis by regulating microglia phenotypes via the GPC4/TLR4/NF-κB signaling axis

Uveitis, a vision-threatening inflammatory disease worldwide, is closely related to resident microglia. Retinal microglia are the main immune effector cells with strong plasticity, but their role in uveitis remains unclear. N6-methyladenosine (m(6)A) modification has been proven to be involved in th...

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Detalles Bibliográficos
Autores principales: He, Siyuan, Li, Wanqian, Wang, Guoqing, Wang, Xiaotang, Fan, Wei, Zhang, Zhi, Li, Na, Hou, Shengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363593/
https://www.ncbi.nlm.nih.gov/pubmed/37492748
http://dx.doi.org/10.1016/j.gendis.2022.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363593/
https://www.ncbi.nlm.nih.gov/pubmed/37492748
http://dx.doi.org/10.1016/j.gendis.2022.09.008

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