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The function and mechanism of lactate and lactylation in tumor metabolism and microenvironment

Lactate is an end product of glycolysis. Owing to the lactate shuttle concept introduced in the early 1980s, increasing researchers indicate lactate as a critical energy source for mitochondrial respiration and as a precursor of gluconeogenesis. Lactate also acts as a multifunctional signaling molec...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Peng, Qiu, Zheng, Jinhua, Yang, Yuzhong, Zhang, Xuemei, Ma, Aiyu, Qin, Yuxia, Qin, Zailong, Zheng, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363641/
https://www.ncbi.nlm.nih.gov/pubmed/37492749
http://dx.doi.org/10.1016/j.gendis.2022.10.006