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Small bowel edema and lymphocytic duodenitis as severe reversible gastrointestinal toxicity of selpercatinib in RET fusion–positive non–small cell lung cancer: a case report

INTRODUCTION: Rearranged during transfection (RET) gene rearrangements occur in 1%–2% of non–small cell lung cancer (NSCLC). Because of the results of the study LIBRETTO-001, selpercatinib has been approved as the first-line treatment for patients with RET fusion–positive advanced NSCLC. Selpercatin...

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Detalles Bibliográficos
Autores principales: Scattolin, Daniela, Scagliori, Elena, Scapinello, Antonio, Fantin, Alberto, Guarneri, Valentina, Pasello, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363725/
https://www.ncbi.nlm.nih.gov/pubmed/37492479
http://dx.doi.org/10.3389/fonc.2023.1201599