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A risk score combining co-expression modules related to myeloid cells and alternative splicing associates with response to PD-1/PD-L1 blockade in non-small cell lung cancer

BACKGROUND: Comprehensive analysis of transcriptomic profiles of non-small cell lung cancer (NSCLC) may provide novel evidence for biomarkers associated with response to PD-1/PD-L1 immune checkpoint blockade (ICB). METHODS: We utilized weighted gene co-expression network analysis (WGCNA) to analyze...

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Detalles Bibliográficos
Autores principales: Han, Yichao, Liu, Si-Yang Maggie, Jin, Runsen, Meng, Wangyang, Wu, Yi-Long, Li, Hecheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363729/
https://www.ncbi.nlm.nih.gov/pubmed/37492578
http://dx.doi.org/10.3389/fimmu.2023.1178193