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Single-cell transcriptomic landscape of immunometabolism reveals intervention candidates of ascorbate and aldarate metabolism, fatty-acid degradation and PUFA metabolism of T-cell subsets in healthy controls, psoriasis and psoriatic arthritis

INTRODUCTION: The modulation of immunometabolic pathways is emerging as a promising therapeutic target for immune-mediated diseases. However, the immunometabolic features of psoriatic disease and the potential targets for immunometabolic intervention in the different T-cell subsets involved in its p...

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Detalles Bibliográficos
Autores principales: Peng, Lu, Chen, Ling, Wan, Jianji, Liu, Wenqi, Lou, Shuang, Shen, Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363747/
https://www.ncbi.nlm.nih.gov/pubmed/37492568
http://dx.doi.org/10.3389/fimmu.2023.1179877