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Systematic characterization of regulatory variants of blood pressure genes

High blood pressure (BP) is the major risk factor for cardiovascular disease. Genome-wide association studies have identified genetic variants for BP, but functional insights into causality and related molecular mechanisms lag behind. We functionally characterize 4,608 genetic variants in linkage wi...

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Detalles Bibliográficos
Autores principales: Oliveros, Winona, Delfosse, Kate, Lato, Daniella F., Kiriakopulos, Katerina, Mokhtaridoost, Milad, Said, Abdelrahman, McMurray, Brandon J., Browning, Jared W.L., Mattioli, Kaia, Meng, Guoliang, Ellis, James, Mital, Seema, Melé, Marta, Maass, Philipp G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363820/
https://www.ncbi.nlm.nih.gov/pubmed/37492106
http://dx.doi.org/10.1016/j.xgen.2023.100330