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Systematic characterization of regulatory variants of blood pressure genes
High blood pressure (BP) is the major risk factor for cardiovascular disease. Genome-wide association studies have identified genetic variants for BP, but functional insights into causality and related molecular mechanisms lag behind. We functionally characterize 4,608 genetic variants in linkage wi...
Autores principales: | Oliveros, Winona, Delfosse, Kate, Lato, Daniella F., Kiriakopulos, Katerina, Mokhtaridoost, Milad, Said, Abdelrahman, McMurray, Brandon J., Browning, Jared W.L., Mattioli, Kaia, Meng, Guoliang, Ellis, James, Mital, Seema, Melé, Marta, Maass, Philipp G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10363820/ https://www.ncbi.nlm.nih.gov/pubmed/37492106 http://dx.doi.org/10.1016/j.xgen.2023.100330 |
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